Coordinated Initiative in Experimental Medicine

Under the Experimental Medicine funding initiative, UKCRC Partners have provided three strands of funding:

 

The first of these is to support research projects and programmes and the other two are to support research infrastructure.

Support for Research

Supported by the Medical Research Council (MRC) and the British Heart Foundation

In 2005 the MRC provided £15 million investment in grants focusing on the early testing of novel treatments or interventions in human participants. A total of 200 full applications were received, spanning a wide range of disease areas, and the funding decisions were made in March 2006.

Details of the 28 awards made under the scheme can be found on the MRC’s website.

Building on the earlier initiative, the MRC launched a second wave of funding for ‘proof of concept’ studies to continue to strengthen experimental medicine research in the UK. Funding decisions will be made at the end of March 2008 and applicants will be advised of the outcome in April 2008.

The British Heart Foundation partnered with the MRC in the second Call for Proposals which provided further funding of at least £15 million. This is one of a suite of initiatives and funding opportunities available for experimental medicine over the next few years. The next available funding for Experimental Medicine is likely to be announced during 2008.

Experimental Cancer Medicine Centres

Supported by Cancer Research UK and the UK Health Departments.

Cancer Research UK and the UK Health Departments, under the auspices of the National Cancer Research Institute, provided £35 million funding for the establishment of 17 Experimental Cancer Medicine Centres (ECMCs).

These are: Barts and the London, Birmingham, Belfast, Cambridge, Cardiff, Edinburgh, Glasgow, Imperial College, Institute of Cancer Research, King’s College London, Leeds-Bradford-Hull-York, Leicester, Manchester, Newcastle, Oxford, Southampton and University College London. In addition, two further ECMCs in Liverpool and Sheffield have been designated ECMCs in development.

From April 2007, each ECMC will each receive up to £2 million over 5 years, while the Centres in Development will be awarded £150,000 per year. The support will meet infrastructure costs for the early testing of new cancer treatments or interventions in human participants.

More detail on these grants can be found on the websites of Cancer Research UK and the Department of Health.

Clinical Research Infrastructure Initiative

Supported by the Wellcome Trust, Wolfson Foundation, British Heart Foundation, Cancer Research UK, the Medical Research Council (MRC), the Health Departments in England, Northern Ireland, Scotland and Wales, and the Health Research Board of Ireland.

Under a competitive process managed by the Wellcome Trust, the funding partners collectively provided £84 million of new funding under the Clinical Research Infrastructure Initiative (CRII). This initiative was created to provide significant new investment for clinical research infrastructure. Priority areas targeted by the scheme include clinical research facilities, enabling technologies (imaging, proteomics, genomics, diagnostics, devices), capacity for early medicinal chemistry and pharmaceutical support.

The initiative awarded funds to develop and strengthen UK clinical research facilities in Belfast, Birmingham, Cambridge, Edinburgh, The Institute of Cancer Research, Imperial College London, King's College London, Manchester, Newcastle, Oxford and University College London. In addition, a new Clinical Research Centre was established in Dublin, jointly funded by the Wellcome Trust and the Health Research Board of Ireland.

More detail on these grants can be found in the UKCRC press release.

Links:

Overview of Experimental Medicine

National Framework for Experimental Medicine